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https://repositorio.inpa.gov.br/handle/1/16396
Title: | HLA in Brazilian Ashkenazic Jews with chronic dermatophytosis caused by Trichophyton rubrum |
Authors: | Sadahiro, Aya Feresin Moraes, José Roberto Hue Moraes, Maria Elisa Romero, Matilde Lima Gouvea, Nancy Alves de Gouvea, Celso José Ogusku, Maurício Morishi Campbell, Iphis Tenfuss Zaitz, Clarisse |
Keywords: | Trichophyton Rubrum |
Issue Date: | 2004 |
metadata.dc.publisher.journal: | Brazilian Journal of Microbiology |
metadata.dc.relation.ispartof: | Volume 35, Número 1-2, Pags. 69-73 |
Abstract: | The frequency of HLA (Human Leucocyte Antigens) was analyzed in 25 non-consanguineous Brazilian Ashkenazic Jews, resident in the city of São Paulo, Brazil, suffering from chronic dermatophytosis caused by T. rubrum, and in 25 non-infected individuals belonging to the same ethnic group. Statistically significant values (p<0.05) were observed for HLA-B14 associated with resistance to chronic dermatophytosis and HLA-DQB1*06 (p=0.05) possibly related to susceptibility. These findings suggest that genes on the chromosome 6, in the region of the major histocompatibility complex, may influence the development of chronic dermatophytosis. |
metadata.dc.identifier.doi: | 10.1590/S1517-83822004000100011 |
Appears in Collections: | Artigos |
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