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dc.contributor.authorGarcia, Armando da Costa-
dc.contributor.authorMenezes Júnior, Orivaldo Teixeira de-
dc.contributor.authorMariano, Lissa Apolonia-
dc.contributor.authorSantiago, Letícia Corrêa-
dc.contributor.authorAraújo, Ângela Regina-
dc.contributor.authorMonfardini, Julia Dietsche-
dc.contributor.authorSimões, Rejane de Castro-
dc.contributor.authorOliveira, André Correa de-
dc.contributor.authorRoque, Rosemary Aparecida-
dc.contributor.authorTadei, Wanderli Pedro-
dc.contributor.authorTeles, Helder Lopes-
dc.contributor.authorOliveira, Camila Martins de-
dc.date.accessioned2022-12-06T12:52:37Z-
dc.date.available2022-12-06T12:52:37Z-
dc.date.issued2022-
dc.identifier.issn00378682-
dc.identifier.urihttps://repositorio.inpa.gov.br/handle/1/38880-
dc.description.abstractBackground: Aedes aegypti is the primary vector of viruses, such as Zika, chikungunya, yellow fever, and dengue. In this context, a biomonitored chemical study was conducted to evaluate the activity of the crude extract of the endophytic fungus Phomopsis sp. against the larvae of Aedes aegypti. Methods: Crude extract, fractions, and isolated substances were evaluated in in-vitro assays against third-stage larvae of Aedes aegypti. Results: We isolated 3-nitropropionic acid with an LC50 of 15.172 ppm and LC90 of 18.178 ppm after 24 hours of larval exposure. Conclusions: The results indicated that 3-nitropropionic acid exerted larvicidal activity. © 2022, Sociedade Brasileira de Medicina Tropical. All rights reserved.pt_BR
dc.language.isoenpt_BR
dc.relation.ispartofVolume 55pt_BR
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Brazil*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/br/*
dc.subjectBiomonitored chemicalpt_BR
dc.subjectDenguept_BR
dc.subjectAedes aegyptipt_BR
dc.subjectSecondary metabolitept_BR
dc.titleEndophytic fungus Phomopsis sp. as a source of 3-nitropropionic acid with larvicidal activity against Aedes aegypti (Linnaeus 1762, Diptera: Culicidae)pt_BR
dc.typeArtigopt_BR
dc.identifier.doi10.1590/0037-8682-0018-2022-
dc.publisher.journalRevista da Sociedade Brasileira de Medicina Tropicalpt_BR
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