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Identification of primary drug resistance to rifampin in mycobacterium leprae strains from leprosy patients in Amazonas State, Brazil
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Abstract:
The aim of this study was to identify polymorphisms in the folp1, gyrA, and rpoB genes in leprosy patients treated in Amazonas State, Brazil. Among 197 slit-skin smear samples from untreated or relapsed patients, we found three cases of primary resistance to rifampin and one confirmed case of multidrug resistance. Copyright © 2014, American Society for Microbiology. All Rights Reserved.
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Rifampicin, Antiinfective Agent, Bacterial Protein, Rifampicin, Antibiotic Resistance, Bacterial Gene, Bacterial Strain, Dna Sequence, Folp1 Gene, Polymorphism, Genetic, Gyra Gene, Human, Human Tissue, Leprosy, Multidrug Resistance, Mycobacterium Leprae, Nonhuman, Nucleotide Sequence, Rpob Gene, Drug Effects, Female, Genetics, Isolation And Purification, Leprosy, Male, Microbiology, Mycobacterium Leprae, Anti-bacterial Agents, Bacterial Proteins, Drug Resistance, Bacterial, Female, Humans, Leprosy, Male, Mycobacterium Leprae, Polymorphism, Genetic, Rifampin
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Exceto quando indicado de outra forma, a licença deste item é descrita como Attribution-NonCommercial-NoDerivs 3.0 Brazil