Please use this identifier to cite or link to this item:
https://repositorio.inpa.gov.br/handle/1/16019| Title: | Identification of primary drug resistance to rifampin in mycobacterium leprae strains from leprosy patients in Amazonas State, Brazil |
| Authors: | Mejía, Matilde Del Carmen Contreras dos Santos, Maísa Porto Silva, George Allan Villarouco da Motta-Passos, Isabella da Naveca, Felipe Gomes Cunha, Maria Coelho Graça Souza Moraes, Milton Ozório Paula, Lúcia de |
| Keywords: | Rifampicin Antiinfective Agent Bacterial Protein Rifampicin Antibiotic Resistance Bacterial Gene Bacterial Strain Dna Sequence Folp1 Gene Polymorphism, Genetic Gyra Gene Human Human Tissue Leprosy Multidrug Resistance Mycobacterium Leprae Nonhuman Nucleotide Sequence Rpob Gene Drug Effects Female Genetics Isolation And Purification Leprosy Male Microbiology Mycobacterium Leprae Anti-bacterial Agents Bacterial Proteins Drug Resistance, Bacterial Female Humans Leprosy Male Mycobacterium Leprae Polymorphism, Genetic Rifampin |
| Issue Date: | 2014 |
| metadata.dc.publisher.journal: | Journal of Clinical Microbiology |
| metadata.dc.relation.ispartof: | Volume 52, Número 12, Pags. 4359-4360 |
| Abstract: | The aim of this study was to identify polymorphisms in the folp1, gyrA, and rpoB genes in leprosy patients treated in Amazonas State, Brazil. Among 197 slit-skin smear samples from untreated or relapsed patients, we found three cases of primary resistance to rifampin and one confirmed case of multidrug resistance. Copyright © 2014, American Society for Microbiology. All Rights Reserved. |
| metadata.dc.identifier.doi: | 10.1128/JCM.01688-14 |
| Appears in Collections: | Artigos |
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