Please use this identifier to cite or link to this item:
https://repositorio.inpa.gov.br/handle/1/18863
Title: | Production of enokipodins A, B, C, and D: A new group of antimicrobial metabolites from mycelial culture of Flammulina velutipes |
Authors: | Ishikawa, Noemia Kazue Yamaji, Keiko Ishimoto, Hiroshi Miura, Kiyoshi Yukiharu, Fukushi, Takahashi, Kunihide Tahara, Satoshi |
Keywords: | Bacillus Subtilis Bacteria (microorganisms) Bacterium Subtilis Flammulina Velutipes Staphylococcus Aureus |
Issue Date: | 2005 |
metadata.dc.publisher.journal: | Mycoscience |
metadata.dc.relation.ispartof: | Volume 46, Número 1, Pags. 39-45 |
Abstract: | Antimicrobial compounds enokipodins A, B, C, and D were originally isolated from the culture filtrates of Flammulina velutipes mycelial culture. Analysis of antibacterial activity by the paper disk method and quantification of enokipodins A-D by high performance liquid chromatography (HPLC) showed that F. velutipes mycelia produced enokipodins A-D in their late growing phase. Great genetic variability in production of these compounds was observed among ten strains of F. velutipes in analyses of antimicrobial activity by the hole-plate diffusion method and quantification by HPLC. Enokipodins A-D demonstrated antimicrobial activity mainly against the grampositive bacteria Bacillus subtilis and Staphylococcus aureus. Evaluation of minimum inhibitory doses (MIDs) showed that MIDs of enokipodins A and C for B. subtilis were as low as that of the penicillin G antibiotic. © The Mycological Society of Japan and Springer-Verlag Tokyo 2005. |
metadata.dc.identifier.doi: | 10.1007/s10267-004-0208-6 |
Appears in Collections: | Artigos |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.