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Campo DC | Valor | Idioma |
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dc.contributor.author | Schwertz, Maíra Cássia | - |
dc.contributor.author | Maia, Jeniffer Resende Patrocínio | - |
dc.contributor.author | Sousa, Rita Fernandes Cássia P. de | - |
dc.contributor.author | Aguiar, Jaime Paiva Lopes | - |
dc.contributor.author | Yuyama, Lucia Kiyoko Ozaki | - |
dc.contributor.author | Lima, Emerson Silva | - |
dc.date.accessioned | 2020-05-25T19:10:47Z | - |
dc.date.available | 2020-05-25T19:10:47Z | - |
dc.date.issued | 2012 | - |
dc.identifier.uri | https://repositorio.inpa.gov.br/handle/1/16149 | - |
dc.description.abstract | Objective: This study evaluated the potential hypolipidemic effect of camu-camu juice (Myrciaria dubia (Kunth) McVaugh) in dyslipidemic rats. Methods: Seventy-two adult male Wistar rats (Rattus norvegicus var. albinus Berkenhout) with an average weight of 200g were used. The experiment was divided into two phases: induction of dyslipidemia and treatment. Dyslipidemia was induced by a high-fat diet (commercial feed plus 10.0% lard, 1.0% cholesterol and 0.1% cholic acid) given to the animals for 21 days. In the treatment phase, 40 dyslipidemic rats were randomly divided into five groups (n=8). Of these, three were subjected to different treatments with camu-camu juice: 0.4mL.kg-1, 4.0mL.kg-1 and 10mL.kg-1 for 14 days. The other two groups were kept as parameters: a basal group (normolipidemic) and a hyperlipidemic group receiving 10mL.kg-1 of quercetin (standard treatment). The potential hypolipidemic effect of camu-camu juice was assessed by the following measurements: plasma lipoproteins (triacylglycerol, total cholesterol, high density lipoprotein-cholesterol and low density lipoproteincholesterol), fecal and liver cholesterol, and measurements of feed intake and body weight. Results: All dosages of camu-camu juice were hypolipidemic, reducing triacylglycerol, total cholesterol, fecal cholesterol excretion and hepatic cholesterol. The best results were obtained by the 10 mL.kg-1 dosage of camu-camu juice. Rat body weight and food intake did not vary significantly during the treatment. Conclusion Camu-camu juice has a hypolipidemic effect in dyslipidemic rats. These results can be used as reference for future studies on this Amazonian fruit. | en |
dc.language.iso | pt_BR | pt_BR |
dc.relation.ispartof | Volume 25, Número 1, Pags. 35-44 | pt_BR |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Brazil | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/br/ | * |
dc.subject | Animalsia | en |
dc.subject | Myrciaria Dubia | en |
dc.subject | Rattus | en |
dc.subject | Rattus Norvegicus | en |
dc.title | Hypolipidemic effect of camu-camu juice in rats | en |
dc.title.alternative | Efeito hipolipidêmico do suco de camu-camu em ratos | pt_BR |
dc.type | Artigo | pt_BR |
dc.identifier.doi | 10.1590/S1415-52732012000100004 | - |
dc.publisher.journal | Revista de Nutrição | pt_BR |
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