Use este identificador para citar ou linkar para este item:
https://repositorio.inpa.gov.br/handle/1/16195
Registro completo de metadados
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Dam, Tarun Kanti | - |
dc.contributor.author | Cavada, B. S. | - |
dc.contributor.author | Nagano, C. S. | - |
dc.contributor.author | Rocha, Bruno Anderson Matias da | - |
dc.contributor.author | Benevides, R. G. | - |
dc.contributor.author | Nascimento, K. S. | - |
dc.contributor.author | Sousa, Luiz A.G. de | - |
dc.contributor.author | Oscarson, Stefan | - |
dc.contributor.author | Brewer, Curtis Fred | - |
dc.date.accessioned | 2020-05-31T18:05:40Z | - |
dc.date.available | 2020-05-31T18:05:40Z | - |
dc.date.issued | 2011 | - |
dc.identifier.uri | https://repositorio.inpa.gov.br/handle/1/16195 | - |
dc.description.abstract | The legume species of Cymbosema roseum of Diocleinae subtribe produce at least two different seed lectins. The present study demonstrates that C. roseum lectin I (CRL I) binds with high affinity to the "core" trimannoside of N-linked oligosaccharides. Cymbosema roseum lectin II (CRL II), on the other hand, binds with high affinity to the blood group H trisaccharide (Fuc1,2Gal1-4GlcNAc-). Thermodynamic and hemagglutination inhibition studies reveal the fine binding specificities of the two lectins. Data obtained with a complete set of monodeoxy analogs of the core trimannoside indicate that CRL I recognizes the 3-, 4- and 6-hydroxyl groups of the (1,6) Man residue, the 3- and 4-hydroxyl group of the (1,3) Man residue and the 2- and 4-hydroxyl groups of the central Man residue of the trimannoside. CRL I possesses enhanced affinities for the Man5 oligomannose glycan and a biantennary complex glycan as well as glycoproteins containing high-mannose glycans. On the other hand, CRL II distinguishes the blood group H type II epitope from the Lewisx, Lewisy, Lewisa and Lewisb epitopes. CRL II also distinguishes between blood group H type II and type I trisaccharides. CRL I and CRL II, respectively, possess differences in fine specificities when compared with other reported mannose and fucose recognizing lectins. This is the first report of a mannose-specific lectin (CRL I) and a blood group H type II-specific lectin (CRL II) from seeds of a member of the Diocleinae subtribe. © 2011 The Author. | en |
dc.language.iso | en | pt_BR |
dc.relation.ispartof | Volume 21, Número 7, Pags. 925-933 | pt_BR |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Brazil | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/br/ | * |
dc.subject | Blood Group H Antigen | en |
dc.subject | Epitope | en |
dc.subject | Fucose | en |
dc.subject | Lectin | en |
dc.subject | Mannose Oligosaccharide | en |
dc.subject | Trisaccharide | en |
dc.subject | Chemical Structure | en |
dc.subject | Cymbosema Roseum | en |
dc.subject | Hemagglutination | en |
dc.subject | Legume | en |
dc.subject | Nonhuman | en |
dc.subject | Seed Plant | en |
dc.subject | Priority Journal | en |
dc.subject | Protein Binding | en |
dc.subject | Protein Purification | en |
dc.subject | Thermodynamics | en |
dc.subject | Abo Blood-group System | en |
dc.subject | Animal | en |
dc.subject | Chromatography, Affinity | en |
dc.subject | Erythrocytes | en |
dc.subject | Fabaceae | en |
dc.subject | Fucose | en |
dc.subject | Hemagglutination Inhibition Tests | en |
dc.subject | Mannose | en |
dc.subject | Mannose-binding Lectins | en |
dc.subject | Oligosaccharides | en |
dc.subject | Plant Lectins | en |
dc.subject | Polysaccharides | en |
dc.subject | Rabbits | en |
dc.subject | Seeds | en |
dc.subject | Thermodynamics | en |
dc.subject | Cymbosema Roseum | en |
dc.title | Fine specificities of two lectins from Cymbosema roseum seeds: A lectin specific for high-mannose oligosaccharides and a lectin specific for blood group H type II trisaccharide | en |
dc.type | Artigo | pt_BR |
dc.identifier.doi | 10.1093/glycob/cwr025 | - |
dc.publisher.journal | Glycobiology | pt_BR |
Aparece nas coleções: | Artigos |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
---|---|---|---|---|
artigo-inpa.pdf | 426,46 kB | Adobe PDF | Visualizar/Abrir |
Este item está licenciada sob uma Licença Creative Commons