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https://repositorio.inpa.gov.br/handle/1/18663
Título: | The biological activity of extracts, hydrolates, and volatile oils of Aniba duckei Kostermans and the quantification of linalol in the leaf hydrolate |
Título(s) alternativo(s): | Atividade biológica de extratos, hidrolatos e óleos voláteis de pau-rosa (Aniba duckei Kostermans) e quantificaç ão do linalol no hidrolato de folhas |
Autor: | Souza, K. S. Chaar, Jamal da Silva Oliveira, Kelson Mota Teixeira de Gomes, E. O. Portela, Cíntia Nicácio Pohlit, Adrian Martin Quignard, Etienne Louis Jacques Nunomura, Sergio Massayoshi Tadei, Wanderli Pedro Mouchrek Filho, Victor Elias Silva, D. D. Galhiane, Mário Sérgio Chierice, Gilberto Orivaldo |
Palavras-chave: | Aniba Duckei Extract Essential Oil Larvicidal Agent Linalool Plant Extract Unclassified Drug Aedes Aegypti Angiosperm Aniba Duckei Artemia Cytotoxicity Dengue Dilution Drug Activity Hemorrhagic Fever In Vitro Study Larva Nonhuman Quantitative Analysis Aedes Aegypti Aniba Artemia Franciscana Lauraceae |
Data do documento: | 2007 |
Revista: | Revista Brasileira de Plantas Medicinais |
É parte de: | Volume 9, Número 2, Pags. 1-7 |
Abstract: | The objective of this study was to evaluate the bioactivity of extracts and by-products of volatile oil extraction from rosewood, as well as to quantify linalool levels in hydrolates. Branch and trunkwood methanol extracts presented significant lethality to Artemia franciscana larvae (LC 50 58 ± 33 and 71 ± 31 mg mL -1, respectively). Hydrolates (diluted to 25%) and volatile oil (2 mg mL -1) caused 100% mortality. These results show that A. duckei is a potential source of cytotoxic substances. The volatile oil obtained from branchwood presented larvicidal activity in vitro towards Aedes aegypti (hemorrhagic dengue fever vector, LC 50 2,2 g L -1). Quantitative GC analysis performed on the hydrolate obtained from leaf extraction revealed a linalool concentration of 0.09% v/v (6 mM), which could be responsible for the observed bioactivity. |
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