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|dc.contributor.author||Kamunde, Collins N.||-|
|dc.contributor.author||Matsuo, Aline Y.O.||-|
|dc.contributor.author||Wood, Chris M.||-|
|dc.description.abstract||The effects of elevated dietary calcium (as CaCO3) and acute waterborne Cd exposure (50 μg/l) on whole body uptake, tissue uptake, and internal distribution of newly accumulated Cd, Ca2+, and Na + in juvenile rainbow trout were examined. Fish were fed with three diets (mg Ca2+/g food): 20 (control), 30 and 60 for 7 days before fluxes were measured with radiotracers. The highest dietary Ca2+ elevation reduced waterborne whole body Ca2+ uptake, but did not protect against inhibition of waterborne Ca2+ uptake by waterborne Cd. Both Ca2+-supplemented diets reduced newly accumulated Ca 2+ in the gills in relation to the control treatment, but did not prevent the Cd-inhibiting effect against accumulation of new Ca2+ in most compartments. Fish fed with Ca2+-supplemented diets showed markedly lower rates of whole body uptake and internalization (in some tissues) of waterborne Cd, illustrating that, while dietary Ca2+ supplementation did not protect against the impact of waterborne Cd on waterborne Ca2+ uptake, it did protect against the uptake of Cd. Waterborne Cd had no effect on Na+ fluxes, total Cl-, and in most body compartments, newly accumulated Na+ and total Na + were also not affected. Dietary supplementation with CaCO 3 had the same protective effect as demonstrated by dietary supplementation with CaCl2 in an earlier study. Thus, the reduction of waterborne Cd uptake and internalization by dietary Ca2+ was specifically due to Ca2+ and not to the anion. © 2004 Elsevier Inc. All rights reserved.||en|
|dc.relation.ispartof||Volume 137, Número 4, Pags. 363-372||pt_BR|
|dc.subject||Calcium Blood Level||en|
|dc.title||Acute waterborne cadmium uptake in rainbow trout is reduced by dietary calcium carbonate||en|
|dc.publisher.journal||Comparative Biochemistry and Physiology - C Toxicology and Pharmacology||pt_BR|
|Appears in Collections:||Artigos|
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