Please use this identifier to cite or link to this item:
Title: Evolutionary trends of LDH isozymes in fishes
Authors: Val, Vera Maria Fonseca Almeida e
Val, Adalberto Luis
Keywords: Lactate Dehydrogenase Isoenzyme
Priority Journal
Issue Date: 1993
metadata.dc.publisher.journal: Comparative Biochemistry and Physiology -- Part B: Biochemistry and
metadata.dc.relation.ispartof: Volume 105, Número 1, Pags. 21-28
Abstract: 1. 1. LDH characteristics (loci numbers, number of isozymes constituted by A and B subunits, and tissue specificity of LDH-C4) were reviewed for 245 fish species. 2. 2. The occurrence of different isozyme numbers among species of a single family (e.g. 3, 4 and 5 banded patterns), plus the existence of alleles generating 4 or 5 banded patterns in a single population indicate that the number of LDH isozymes constituted by A and B subunits might not be a character under selective pressure. 3. 3. The regulatory pattern of LDH-C* gene, i.e. its occurrence in several tissues of primitive fishes plus its highly restricted tissue distribution in advanced teleost, and even its absence in some intermediate groups (e.g. Characiformes and Siluriformes) suggest a possible selective pressure upon an ancient gene. 4. 4. Four evolutionary trends are suggested considering isozyme tissue distribution as well as LDH physiological role: (i) convergence of B to A subunit as in good anaerobes; (ii) restriction of B subunits in advanced teleost, resulting in the same pattern as in (i); (iii) non-divergence between A and B subunit as occurs in some Amazon fishes which are obligatory aerobes and (iv) the restriction of C subunit to specific tissues in advanced teleost reaching a high specialization degree, which physiological meaning is not explained yet. © 1993.
metadata.dc.identifier.doi: 10.1016/0305-0491(93)90164-Z
Appears in Collections:Artigos

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.