| Title: | Confirmed invasive pulmonary aspergillosis and COVID-19: The value of postmortem findings to support antemortem management |
| Authors: | Santana, Monique Freire
Pivoto, Guilherme
Alexandre, Márcia Almeida A.Araújo
Baía-Da-Silva, Djane Clarys
Borba, Mayla Gabriela Da Silva
Val, Fernando Almeida
Brito-Sousa, José Diego
Melo, Gisely Cardoso de
Monteiro, Wuelton Marcelo
Souza, João Vicente Braga
Pinheiro, Silviane Bezerra
Ferreira, Luiz Carlos Lima
Naveca, Felipe Gomes
Nascimento, Valdinete Alves
Corado, André Lima Guerra
Hajjar, Ludhmila Abrahao
Neto, João Ricardo Silva
Siva, George Alan Villarouco
Pasqualotto, Alessandro
Lacerda, Marcus V. G. |
| Keywords: | azithromycin
C reactive protein
ceftriaxone
chloroquine
creatinine
enoxaparin
furosemide
internal transcribed spacer 1
internal transcribed spacer 2
noradrenalin
oseltamivir
ribosome DNA
urea
vasoactive agent
Aged
Article
artificial ventilation
Aspergillus
Aspergillus penicillioides
Autopsy
bradycardia
bronchopneumonia
case report
clinical article
coronavirus disease 2019
cyanosis
endotracheal intubation
hematocrit
histopathology
human
human tissue
hypotension
invasive aspergillosis
lung infiltrate
lymphocytopenia
Male
neutrophilia
nucleotide sequence
polymerase chain reaction
positive end expiratory pressure
real time reverse transcription polymerase chain reaction
thorax radiography
Autopsy
Betacoronavirus
complication
Coronavirus infection
fatality
Genetics
invasive aspergillosis
isolation and purification
Lung
microbiology
pandemic
pathology
virus pneumonia
Aged
Aspergillus
Autopsy
Betacoronavirus
Coronavirus Infections
Fatal Outcome
Humans
Invasive Pulmonary Aspergillosis
Lung
Male
Pandemics
Pneumonia, Viral |
| Issue Date: | 2020 |
| metadata.dc.publisher.journal: | Revista da Sociedade Brasileira de Medicina Tropical |
| metadata.dc.relation.ispartof: | Volume 53, Número , pgs. 1-4 |
| metadata.dc.description.resumo: | We present postmortem evidence of invasive pulmonary aspergillosis (IPA) in a patient with severe COVID-19. Autopsies of COVID-19 confirmed cases were performed. The patient died despite antimicrobials, mechanical ventilation, and vasopressor support. Histopathology and peripheral blood galactomannan antigen testing confirmed IPA. Aspergillus penicillioides infection was confirmed by nucleotide sequencing and BLAST analysis. Further reports are needed to assess the occurrence and frequency of IPA in SARS-CoV-2 infections, and how they interact clinically. © 2020, Sociedade Brasileira de Medicina Tropical. All rights reserved. |
| metadata.dc.identifier.doi: | 10.1590/0037-8682-0401-2020 |
| Appears in Collections: | Artigos
|
