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Title: Htlv-2 infection in manaus, brazil: First description of htlv-2c subtype in an urban area of the western amazon region
Authors: Pontes, Gemilson Soares
Ribeiro, Hygor Halyson Figueiredo
Toro, Diana Mota
Neto, José Pereira De Moura
Souza, Victor C.
de Almeida, Maria Edilene Martins
Nascimento, Valdinete Alves do
Costa, Cristóvão Alves da
Naveca, Felipe Gomes
Santos, Mike Barbosa
Vallinoto, Antônio Carlos Rosário
Issue Date: 2020
metadata.dc.publisher.journal: Revista da Sociedade Brasileira de Medicina Tropical
metadata.dc.relation.ispartof: Volume 54, Número
Abstract: Introduction: We investigated the prevalence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) infection in patients with hematological diseases from the western Amazon region of Brazil. Methods: Samples from 306 patients were submitted for the molecular diagnosis of HTLV-1/2 infection by real time PCR (qPCR), with amplification, sequencing, and phylogenetic analysis of the long terminal repeat (LTR) region. Results: A 29-year-old male carrier of sickle cell anemia with a history of multiple blood transfusions was diagnosed with the HTLV-2c subtype. Conclusions: This study describes the first known occurrence of HTLV-2c in the urban area of Brazil’s western Amazon region. © 2020, Sociedade Brasileira de Medicina Tropical. All rights reserved.
metadata.dc.identifier.doi: 10.1590/0037-8682-0066-2020
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