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https://repositorio.inpa.gov.br/handle/1/37797
Título: | Crotalus Durissus Ruruima: Current Knowledge on Natural History, Medical Importance, and Clinical Toxinology |
Autor: | Pucca, Manuela Berto Bernarde, Paulo Sérgio Rocha, Anderson Maciel Viana, Patrik Ferreira Farias, Raimundo Erasmo Souza Cerni, Felipe Augusto Oliveira, Isadora Sousa De Ferreira, Isabela Gobbo Sandri, Eliseu A. Sachett, Jacqueline Almeida Gonçalves Wen, Fanhui Sampaio, Vanderson S. |
Palavras-chave: | Antivenom Crotalus durissus Crotalus durissus ruruima Envenoming |
Data do documento: | 2021 |
Revista: | Frontiers in Immunology |
É parte de: | Volume 12 Número 659515 |
Abstract: | Crotalus durissus ruruima is a rattlesnake subspecies mainly found in Roraima, the northernmost state of Brazil. Envenomings caused by this subspecies lead to severe clinical manifestations (e.g. respiratory muscle paralysis, rhabdomyolysis, and acute renal failure) that can lead to the victim’s death. In this review, we comprehensively describe C. d. ruruima biology and the challenges this subspecies poses for human health, including morphology, distribution, epidemiology, venom cocktail, clinical envenoming, and the current and future specific treatment of envenomings by this snake. Moreover, this review presents maps of the distribution of the snake subspecies and evidence that this species is responsible for some of the most severe envenomings in the country and causes the highest lethality rates. Finally, we also discuss the efficacy of the Brazilian horse-derived antivenoms to treat C. d. ruruima envenomings in Roraima state. © Copyright © 2021 Pucca, Bernarde, Rocha, Viana, Farias, Cerni, Oliveira, Ferreira, Sandri, Sachett, Wen, Sampaio, Laustsen, Sartim and Monteiro. |
DOI: | 10.3389/fimmu.2021.659515 |
Aparece nas coleções: | Artigos |
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