Please use this identifier to cite or link to this item: https://repositorio.inpa.gov.br/handle/1/38247
Title: One Health Implications of Antimicrobial Resistance in Bacteria from Amazon River Dolphins
Authors: Freitas, Alyne Soares
Ocadaque, Crister José
Marigo, Juliana
Carmo, Nívia A.S. do
Gravena, Waleska
Amaral, Rodrigo de Souza
Silva, Vera Maria Ferreira da
Costa, Marcelo Oliveira da
Marmontel, Míriam
Carvalho, Vítor Luz
Diógenes, Expedito Maia
Rocha, Marcos Fábio Gadelha
Keywords: Enterobacterales
Freshwater
Issue Date: 2021
metadata.dc.publisher.journal: EcoHealth
Abstract: Studies on the microbiota of freshwater cetaceans are scarce and may provide important data on animal and environmental health. This study aimed to evaluate the antimicrobial susceptibility of Gram-negative bacteria recovered from two populations of free-ranging Amazon river dolphins (Inia geoffrensis). Twenty-one animals were captured and released, 13 from Negro River and 8 from Tapajós River, Brazil. Swab samples were obtained from the oral cavity, blowhole, genital opening and rectum and were cultured on MacConkey agar. Isolates were biochemically identified, and antimicrobial susceptibility was assessed by disk diffusion method. Overall, 132 isolates were recovered, of which 71 were recovered from animals from Negro River and 61 from Tapajós River. The most commonly recovered bacterial species were Enterobacter cloacae, Morganella morganii, Klebsiella pneumoniae and Pseudomonas aeruginosa. Overall, 51.6% (63/122) of the isolates were not-susceptible (intermediate resistance and resistance), of which 28/122 (22.9%) were resistant to at least one antimicrobial. Cephalothin, cefuroxime and cefepime were the drugs to which more resistant and intermediate results were observed (P < 0.001). The results indicate that free-ranging Amazon river dolphins host resistant bacteria, contributing for their maintenance in the environment. This study highlights the importance of the One Health approach to monitor the emergence of antimicrobial resistance. Summary Gram-negative bacteria recovered from 21 free-ranging Amazon river dolphins (Inia geoffrensis) from the Negro River and the Tapajós River populations were evaluated for their antimicrobial susceptibility. Overall, 51.6% (63/122) of the isolates were not-susceptible (intermediate resistance and resistance), of which 28/122 (22.9%) were resistant to at least one antimicrobial. Cephalothin, cefuroxime and cefepime were the drugs to which more resistant and intermediate results were observed. Thus, free-ranging Amazon river dolphins, never treated with antimicrobials, host resistant bacteria, contributing for their maintenance in the environment and highlighting the importance of the One Health approach to monitor the emergence of antimicrobial resistance. © 2021, EcoHealth Alliance.
metadata.dc.identifier.doi: 10.1007/s10393-021-01558-4
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