Insecticidal and genotoxic potential of two semi-synthetic derivatives of dillapiole for the control of Aedes (Stegomyia) aegypti (Diptera: Culicidae)

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dc.contributor.authorDomingos, Pedro Rauel Cândido
dc.contributor.authorPinto, Ana Cristina da Silva
dc.contributor.authorSantos, Joselita Maria Mendes dos
dc.contributor.authorRafael, Míriam Silva
dc.date.accessioned2020-06-15T21:48:26Z
dc.date.available2020-06-15T21:48:26Z
dc.date.issued2014
dc.description.abstractThe effects of two semi-synthetic dillapiole derivatives, ethyl-ether dillapiole and n-butyl ether dillapiole, on eggs and larvae of Aedes aegypti were studied in view of the need for expansion and renovation of strategic action to control this mosquito - the vector of Dengue virus -, which currently shows a high resistance to chemical insecticides. Eggs and third-instar larvae of A. aegypti that had been exposed to different concentrations of these two compounds showed toxicity and susceptibility, with 100% mortality. Classical cytogenetic assays showed genotoxicity caused by the two compounds in A. aegypti from the cumulative effect of nuclear abnormalities, indicating that these derivatives may be potential alternatives to control A. aegypti. © 2014.en
dc.identifier.doi10.1016/j.mrgentox.2014.07.008
dc.identifier.urihttps://repositorio.inpa.gov.br/handle/1/17593
dc.language.isoenpt_BR
dc.publisher.journalMutation Research - Genetic Toxicology and Environmental Mutagenesispt_BR
dc.relation.ispartofVolume 772, Pags. 42-54pt_BR
dc.rightsRestrito*
dc.subjectDill Apioleen
dc.subjectDill Apiole Derivativeen
dc.subjectLarvicidal Agenten
dc.subjectUnclassified Drugen
dc.subject1,3 Dioxolane Derivativeen
dc.subject5-allyl 6,7-dimethoxy 1,3-benzodioxoleen
dc.subjectAllyl Compounden
dc.subjectInsecticideen
dc.subjectAdulten
dc.subjectAedes Aegyptien
dc.subjectCell Divisionen
dc.subjectControlled Studyen
dc.subjectCytotoxicityen
dc.subjectEgg Layingen
dc.subjectFemaleen
dc.subjectGenotoxicityen
dc.subjectInsecticidal Activityen
dc.subjectInterphaseen
dc.subjectLarvaen
dc.subjectLc50en
dc.subjectNeuroblasten
dc.subjectNonhumanen
dc.subjectOocyteen
dc.subjectPriority Journalen
dc.subjectVector Controlen
dc.subjectAedesen
dc.subjectAnimalsen
dc.subjectChemistryen
dc.subjectDengue Virusen
dc.subjectDisease Carrieren
dc.subjectDna Damageen
dc.subjectMetabolismen
dc.subjectSynthesisen
dc.subjectVirologyen
dc.subjectAedesen
dc.subjectAllyl Compoundsen
dc.subjectAnimalen
dc.subjectDengue Virusen
dc.subjectDioxolesen
dc.subjectDna Damageen
dc.subjectInsect Vectorsen
dc.subjectInsecticidesen
dc.titleInsecticidal and genotoxic potential of two semi-synthetic derivatives of dillapiole for the control of Aedes (Stegomyia) aegypti (Diptera: Culicidae)en
dc.typeArtigopt_BR

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