Eusiderins and other neolignans from an Aniba species

Abstract

A previous report disclosed the presence of benzodioxan and bicyclo[3.2.1]octanoid neolignans in the benzene extract of the trunk wood of an Amazonian Aniba (Lauraceae) species. The chloroform extract of the same material contains additionally two new benzodioxan neolignans [rel-(7S,8R)-Δ8′-7-hydroxy-3,4,5,5′-tetrame thoxy-7.0.3′,8.0.4′-neolignan; rel-(7R,8R)-Δ7′-3,4,5,5′-tetramethoxy- 9′-oxo-7.0.3′,8.0.4′-neolignan], two new bicyclo[3.2.1]-octanoid neolignans [(7R,8S,1′S,2′S,3′S,4′R)-Δ8′-2′,4′-dihydroxy-3,3′-dimethoxy-4,5- methylenedioxy- 1′,2′,3′,4′,5′,6′-hexahydro-5′ -oxo-7.3′,8.1′-neolignan; (7R,8S,1′R,2′S,3′S)-Δ8′ -2′-hydroxy-3,3′,5′-trimethoxy-4,5-methylenedioxy- 1′,2′,3′,4′-tetrahydro-4′-oxo-7.3′ ,8.1′-ne olignan] and a hydrobenzofuranoid neolignan [(7S,8R,1′S,5′S)-Δ8′-3,3′, 5′-tri-methoxy-4,5-methylenedioxy-1′,4′,5′ ,6′-tetrahydro-4′-oxo-7.0.2′,8.1-neolignan]. © 1986.