Improvement of a PCR test to diagnose infection by Mansonella ozzardi

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dc.contributor.authorVera, Luana Janaína Souza
dc.contributor.authorBasano, Sérgio de Almeida
dc.contributor.authorCamargo, Juliana de Souza Almeida Aranha
dc.contributor.authorFrança, Andonai Krauze de
dc.contributor.authorGodoi Matos Ferreira, Ricardo de
dc.contributor.authorCasseb, Almeida Andrade
dc.contributor.authorMedeiros, Jansen Fernandes de
dc.contributor.authorFontes, Gilberto
dc.contributor.authorCamargo, Luis Marcelo Aranha
dc.date.accessioned2020-05-07T14:08:25Z
dc.date.available2020-05-07T14:08:25Z
dc.date.issued2011
dc.description.abstractIntroduction: Mansonelliasis is caused by Mansonella ozzardi. It is widespread in the Amazon region, with a high prevalence. Te common exam of thick blood smears stained with Giemsa shows low efficacy levels and has been an obstacle to diagnosing individuals with low blood parasitemia. Methods: In order to increase diagnosis efcacy, the PCR technique was improved. Results and Conclusions: PCR demonstrated the best performance, with sensitivity and negative predictive values (NPV) of 100%, followed by blood fltration through membrane filters, which showed a sensitivity of 88.9% and a NPV of 84.6%, when compared to thick blood smears.en
dc.identifier.doi10.1590/S0037-86822011000300023
dc.identifier.urihttps://repositorio.inpa.gov.br/handle/1/15158
dc.language.isopt_BRpt_BR
dc.publisher.journalRevista da Sociedade Brasileira de Medicina Tropicalpt_BR
dc.relation.ispartofVolume 44, Número 3, Pags. 380-382pt_BR
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Brazil*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/br/*
dc.subjectBlood Smearen
dc.subjectClinical Clinical Effectivenessen
dc.subjectControlled Studyen
dc.subjectCost Effectiveness Analysisen
dc.subjectDiagnostic Testen
dc.subjectDiagnostic Test Accuracy Studyen
dc.subjectGiemsa Stainen
dc.subjectGold Standarden
dc.subjectHumanen
dc.subjectIntermethod Comparisonen
dc.subjectMansonella Ozzardien
dc.subjectMansonelliasisen
dc.subjectMembrane Filteren
dc.subjectNonhumanen
dc.subjectNucleotide Sequenceen
dc.subjectPerformance Measurement Systemen
dc.subjectPolycarbonate Membrane Filteren
dc.subjectPolymerase Chain Reactionen
dc.subjectPredictive Valueen
dc.subjectSensitivity And Specificityen
dc.subjectMansonella Ozzardien
dc.subjectNucleopolyhedrovirusen
dc.titleImprovement of a PCR test to diagnose infection by Mansonella ozzardipt_BR
dc.title.alternativeAdequação da técnica da PCR para diagnóstico de infecção de Mansonella ozzardipt_BR
dc.typeArtigopt_BR

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