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Campo DC | Valor | Idioma |
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dc.contributor.author | Morais, Márcia Poinho Encarnação de | - |
dc.contributor.author | Gato, Cynara Melo | - |
dc.contributor.author | Maciel, Lucinei Alves | - |
dc.contributor.author | Lalwani, Pritesh | - |
dc.contributor.author | Costa, Cristóvão Alves | - |
dc.contributor.author | Lalwani, Jaila Dias Borges | - |
dc.date.accessioned | 2020-05-18T20:46:09Z | - |
dc.date.available | 2020-05-18T20:46:09Z | - |
dc.date.issued | 2017 | - |
dc.identifier.uri | https://repositorio.inpa.gov.br/handle/1/15774 | - |
dc.description.abstract | Introduction: Human T-lymphotropic virus type 1 and 2 (HTLV-1/2) is endemic in Brazil, but few studies have investigated the seroprevalence of HTLV and its subtypes among blood donors in the capital city Manaus, Amazonas State, Brazil. Aim: To estimate the seroprevalence of HTLV-1/2 and to identify circulating subtypes among blood donors in Manaus. Materials and Methods: Blood donors (2001-2003) were screened for HTLV-1/2 antibodies by ELISA. Positive results were confirmed and subtyped by Western blot assays. Prevalence rates were calculated and compared with demographic data. Results: Among the 87,402 individuals screened, 116 (0.13%) were seropositive for HTLV-1/2. A second sample (76/116) was collected and retested by HTLV-1/2 ELISA, of which only 41/76 were positive. Western blot confirmed HTLV infection in 24/41 retested blood donors [HTLV-1 (n=16), HTLV-2 (n=5) and HTLV-untypable (n=3)]. Discussion: HTLV-1 and HTLV-2 are prevalent among blood donors in Manaus. However, additional studies are needed to comprehend the epidemiology of HTLV-1/2 in Amazonas not only to understand the pathophysiology of the disease providing adequate medical assistance, but also to reduce or block virus transmission. © 2017, Instituto de Medicina Tropical de Sao Paulo. All rights reserved. | en |
dc.language.iso | en | pt_BR |
dc.relation.ispartof | Volume 59 | pt_BR |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Brazil | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/br/ | * |
dc.subject | Adult | en |
dc.subject | Blood Donor | en |
dc.subject | Cross-sectional Study | en |
dc.subject | Enzyme-linked Immunosorbent Assay | en |
dc.subject | Female | en |
dc.subject | Htlv-1 Infection | en |
dc.subject | Htlv-2 Infection | en |
dc.subject | Human | en |
dc.subject | Human T-lymphotropic Virus 1 | en |
dc.subject | Major Clinical Study | en |
dc.subject | Male | en |
dc.subject | Primate T-lymphotropic Virus 2 | en |
dc.subject | Seroprevalence | en |
dc.subject | Social Status | en |
dc.subject | Structured Questionnaire | en |
dc.subject | Western Blotting | en |
dc.subject | Adolescent | en |
dc.subject | Blood Donor | en |
dc.subject | Human T-lymphotropic Virus 1 | en |
dc.subject | Human T-lymphotropic Virus 2 | en |
dc.subject | Isolation And Purification | en |
dc.subject | Middle Aged | en |
dc.subject | Prevalence | en |
dc.subject | Seroepidemiology | en |
dc.subject | Statistics And Numerical Data | en |
dc.subject | Virology | en |
dc.subject | Young Adult | en |
dc.subject | Adolescent | en |
dc.subject | Adult | en |
dc.subject | Blood Donors | en |
dc.subject | Western Blotting | en |
dc.subject | Cross-sectional Studies | en |
dc.subject | Enzyme-linked Immunosorbent Assay | en |
dc.subject | Female | en |
dc.subject | Htlv-ii Infections | en |
dc.subject | Htlv-ii Infections | en |
dc.subject | Human T-lymphotropic Virus 1 | en |
dc.subject | Human T-lymphotropic Virus 2 | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Prevalence | en |
dc.subject | Seroepidemiologic Studies | en |
dc.subject | Young Adult | en |
dc.title | Prevalence of human T-lymphotropic virus type 1 and 2 among blood donors in Manaus, Amazonas State, Brazil | en |
dc.type | Artigo | pt_BR |
dc.identifier.doi | 10.1590/S1678-9946201759080 | - |
dc.publisher.journal | Revista do Instituto de Medicina Tropical de Sao Paulo | pt_BR |
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