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Title: HLA in Brazilian Ashkenazic Jews with chronic dermatophytosis caused by Trichophyton rubrum
Authors: Sadahiro, Aya
Feresin Moraes, José Roberto
Hue Moraes, Maria Elisa
Romero, Matilde
Lima Gouvea, Nancy Alves de
Gouvea, Celso José
Ogusku, Maurício Morishi
Campbell, Iphis Tenfuss
Zaitz, Clarisse
Keywords: Trichophyton Rubrum
Issue Date: 2004
metadata.dc.publisher.journal: Brazilian Journal of Microbiology
metadata.dc.relation.ispartof: Volume 35, Número 1-2, Pags. 69-73
Abstract: The frequency of HLA (Human Leucocyte Antigens) was analyzed in 25 non-consanguineous Brazilian Ashkenazic Jews, resident in the city of São Paulo, Brazil, suffering from chronic dermatophytosis caused by T. rubrum, and in 25 non-infected individuals belonging to the same ethnic group. Statistically significant values (p<0.05) were observed for HLA-B14 associated with resistance to chronic dermatophytosis and HLA-DQB1*06 (p=0.05) possibly related to susceptibility. These findings suggest that genes on the chromosome 6, in the region of the major histocompatibility complex, may influence the development of chronic dermatophytosis.
metadata.dc.identifier.doi: 10.1590/S1517-83822004000100011
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