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Campo DC | Valor | Idioma |
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dc.contributor.author | Delunardo, Frederico Augusto Cariello | - |
dc.contributor.author | Carvalho, Luciano Rodrigues de | - |
dc.contributor.author | Silva, Bruno Ferreira da | - |
dc.contributor.author | Galão, Michel | - |
dc.contributor.author | Val, Adalberto Luis | - |
dc.contributor.author | Chippari-Gomes, Adriana Regina | - |
dc.date.accessioned | 2020-06-15T21:43:20Z | - |
dc.date.available | 2020-06-15T21:43:20Z | - |
dc.date.issued | 2015 | - |
dc.identifier.uri | https://repositorio.inpa.gov.br/handle/1/17474 | - |
dc.description.abstract | This study explored the suitability of the seahorse Hippocampus reidi (Ginsburg, 1933) for assessing biomarkers of genotoxic effects and its use as a sentinel organism to detect the effects of acute exposure to petroleum hydrocarbons. Fish were exposed to three concentrations of crude oil (10, 20 and 30. g/kg) for 96. h, and the activity of phase II biotransformation enzyme glutathione S-transferase (GST) was measured. In addition, we performed genotoxicity assays, such as comet assay, micronucleus (MN) test and nuclear abnormalities (NA) induction, on the erythrocytes of the fish species. Our results revealed that the inhibition of hepatic GST activity in H. reidi was dependent on increasing crude oil concentrations. In contrast, an increase in the damage index (DI) and MN frequency were observed with increased crude oil concentrations. These results indicate that the alkaline comet assay and micronucleus test were suitable and useful in the evaluation of the genotoxicity of crude oil, which could improve determinations of the impact of oil spills on fish populations. In addition, H. reidi is a promising "sentinel organism" to detect the genotoxic impact of petroleum hydrocarbons. © 2015. | en |
dc.language.iso | en | pt_BR |
dc.relation.ispartof | Volume 117, Pags. 28-33 | pt_BR |
dc.rights | Restrito | * |
dc.subject | Glutathione Transferase | en |
dc.subject | Petroleum | en |
dc.subject | Glutathione Transferase | en |
dc.subject | Leukotriene-c4 Synthase | en |
dc.subject | Petroleum | en |
dc.subject | Water Pollutant | en |
dc.subject | Bioindicator | en |
dc.subject | Biomarker | en |
dc.subject | Biotransformation | en |
dc.subject | Crude Oil | en |
dc.subject | Fish | en |
dc.subject | Genotoxicity | en |
dc.subject | Inhibition | en |
dc.subject | Oil Spills | en |
dc.subject | Petroleum Hydrocarbon | en |
dc.subject | Pollution Exposure | en |
dc.subject | Adult | en |
dc.subject | Animals Cell | en |
dc.subject | Biotransformation | en |
dc.subject | Comet Assay | en |
dc.subject | Concentration (parameters) | en |
dc.subject | Controlled Study | en |
dc.subject | Ecotoxicity | en |
dc.subject | Environmental Exposure | en |
dc.subject | Enzyme Activity | en |
dc.subject | Enzyme Inhibition | en |
dc.subject | Fish | en |
dc.subject | Genotoxicity | en |
dc.subject | Hippocampus Reidi | en |
dc.subject | Indicator Organism | en |
dc.subject | Micronucleus Test | en |
dc.subject | Nonhuman | en |
dc.subject | Analysis | en |
dc.subject | Animals | en |
dc.subject | Dna Damage | en |
dc.subject | Drug Effects | en |
dc.subject | Erythrocyte | en |
dc.subject | Evaluation Study | en |
dc.subject | Metabolism | en |
dc.subject | Oil Spills | en |
dc.subject | Smegmamorpha | en |
dc.subject | Toxicity | en |
dc.subject | Water Pollutant | en |
dc.subject | Hippocampus Reidi | en |
dc.subject | Animal | en |
dc.subject | Comet Assay | en |
dc.subject | Dna Damage | en |
dc.subject | Erythrocytes | en |
dc.subject | Glutathione Transferase | en |
dc.subject | Micronucleus Tests | en |
dc.subject | Petroleum | en |
dc.subject | Petroleum Pollution | en |
dc.subject | Smegmamorpha | en |
dc.subject | Water Pollutants, Chemical | en |
dc.title | Seahorse (Hippocampus reidi) as a bioindicator of crude oil exposure | en |
dc.type | Artigo | pt_BR |
dc.identifier.doi | 10.1016/j.ecoenv.2015.03.016 | - |
dc.publisher.journal | Ecotoxicology and Environmental Safety | pt_BR |
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